Doomsday is the fourth episode of the fifth season, and 60th episode overall of the show, Rizzoli & Isles.
A survivalist is believed to have died from halomethane poisoning in his protective fallout shelter, until Maura deems the death "suspicious" since alternative methods to the gas exist today. The team investigates the victim's means of survival if he were to have exited the shelter after a catastrophe. Meanwhile, Angela asks Jane to find out why Frankie is being secretive, but Jane wishes to know the same about Korsak.
- Angie Harmon as Detective Jane Rizzoli
- Sasha Alexander as Dr. Maura Isles
- Jordan Bridges as Officer Frankie Rizzoli, Jr.
- Bruce McGill as Detective Vince Korsak
- Lorraine Bracco as Angela Rizzoli
- Tina Huang as Susie Chang
- Theresa Huang as Cathy Whitehall
- Mike Beaver as Scott Heinz
- Jaime Coll as Officer Garcia
- Michael Dempsey as Bob Murray
- Hayes Ha as Peter Baldwin
- Claude Knowles as Gary Gates
- Alena Savostikova as Violet Nova