Jo Friday Rizzoli is Jane Rizzoli's Yorkshire Terrier. Although Jane did not seem to like animals at all before, she decided to keep Jo after her rescuer, Vincent Korsak, is hospitalized.

In "Don't Hate the Player", Tommy Rizzoli takes her to the veterinarian after he notices that she has been licking her paws too much. The vet diagnoses that Jo is depressed and that her paw-licking is an OCD reflex. However, it is revealed by Korsak that she might just be allergic to the chicken that Angela feeds her.

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