Marisa Rodriguez was Jane Rizzoli's neighbor. Portrayed by Marisa Ramirez, she only made an appearance during the pilot episode, "See One. Do One. Teach One", when she came into Jane's apartment while she was vacuuming. She notes that Jane only vacuums when she has a really tough case, and she also tells Jane that she's having a hard time at law school. They must go way back because Marisa asks Jane to remind her why she wanted to become a lawyer in the first place.

Later, Stark poses as part of the crime unit around Rizolli's apartment and lures her into his and Hoyt's trap by telling her that Marisa is dead. Worried, she gets into their van, only to find Hoyt in the body bag instead of Marisa.